In Brief: AHAs and photoaged skin
This article was originally published in The Rose Sheet
Executive Summary
AHAs and photoaged skin: Study published in the February issue of the Journal of the American Academy of Dermatology concludes that treatment with AHAs "produced significant reversal of epidermal and dermal markers of photoaging." The study, which tested the efficacy of 25% AHA lotion with a pH of 3.5 on photoaged skin in 17 white subjects, found that AHAs "caused an approximate 25% increase in skin thickness" and papillary dermal changes included "improved quality of elastic fibers and increased density of collagen." In addition, "no evidence of inflammation was evident" in the subjects. The participants applied the AHA lotion twice daily on one forearm for "an average of six months" (4-8 month range) while the other arm was treated with placebo. Five subjects were treated with lactic acid; five with glycolic acid; and seven with citric acid. The study was conducted by Cherie Ditre, MD, et al...