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CIR Expert Panel Finalizes 2018 Review Priorities At June Meeting

This article was originally published in The Rose Sheet

Executive Summary

Fourteen cosmetic ingredients are up for first looks by the CIR panel in 2018. Also at its June meeting, the group issued two final ingredient reports and five tentative reports, as well as two insufficient data announcements, and tabled its parabens re-review in order to solicit outside expertise on new DART data.

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Cosmetic Ingredient Review Report Status

Chart: Data compiled by "Rose Sheet" from information in CIR reports following the Expert Panel's June 12-13 meeting.

FDA's OTC Antiseptic Rulemaking Has EWG Eyeing Triclosan In Cosmetics

Triclosan eventually may be eliminated entirely from OTC antiseptic drug products through FDA rulemaking, but it's still used in Colgate Total toothpastes to combat gingivitis and in cosmetics where it functions as a preservative. In a newly published paper, the Environmental Working Group and 200 international scientists and medical professionals express concern about the ingredient's use in those categories as well.

CIR Panel Needs Outside Expertise To Continue Parabens Re-Review

CIR's experts tabled their re-review of parabens safety earlier this month in light of new animal research indicating developmental/reproductive effects in the offspring of rats that were orally administered relatively low butylparaben doses. The panel also issued an insufficient data announcement for preservative polyaminopropyl biguanide.

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